GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6037086 | chr20:25306338 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.37 | 1.21E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037086 | chr20:25306338 | NINL | chr20:25433338-25566153:- | 0.37 | 7.55 | 2.24E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037086 | chr20:25306338 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.71 | 0.000228 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037095 | chr20:25335687 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.7 | 5.92E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037095 | chr20:25335687 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000553 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037095 | chr20:25335687 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.66E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037095 | chr20:25335687 | NINL | chr20:25433338-25566153:- | 0.34 | 7.04 | 6.69E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037095 | chr20:25335687 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.59 | 0.000359 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037099 | chr20:25356876 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.23 | 1.88E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037099 | chr20:25356876 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.49 | 0.000536 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037099 | chr20:25356876 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.06E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037099 | chr20:25356876 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.7E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037099 | chr20:25356876 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.5E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037105 | chr20:25374199 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.23 | 1.88E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6037105 | chr20:25374199 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.49 | 0.000536 | Liver enzyme levels (alkaline phosphatase) |